Angilock 50

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About this item

Angilock 50 is a medicine used to treat high blood pressure and heart disease. Lowering blood pressure helps to prevent future heart attack and stroke. This medicine is also effective in preserving kidney function in patients with diabetes. Angilock 50 can be prescribed either alone or in combination with other medicines. It may be taken with or without food during the day or at night. However, try to take it at the same time each day to get the most benefit. It is important to continue taking it regularly even if you feel well or if your blood pressure is controlled. Most people with high blood pressure do not feel ill, but if you stop taking this medicine, your condition could get worse. This is a widely used medicine and is considered safe for long-term use. Making some changes in your lifestyle will also help lower your blood pressure. These may include regular exercise, losing weight, smoking cessation, reducing alcohol intake, and reducing the amount of salt in your diet as advised by your doctor. This medicine is tolerated well by most patients and has few side effects. Dizziness, particularly after the first dose, is known to occur in some people. This may be associated with headache. Let your doctor know if these side effects bother you or do not go away. No weight gain has been seen with the regular use of this medicine. Before taking this medicine, let your doctor know if you have any kidney or liver problems. Pregnant or breastfeeding mothers should also consult their doctor before taking it. Your doctor may check your kidney function, blood pressure and potassium levels in your blood at regular intervals while you are taking this medicine.

Medicine Overview

Indication:
Diabetic nephropathy, Hypertension, Stroke risk reduction of hypertensive or LVH patients, Heart Failure, Hypertensive Patients with Left Ventricular Hypertrophy

Administration:
May be taken with or without food.

Adult Dose:
Oral Hypertension Adult: 50 mg once daily, may increase to 100 mg/day as single dose or in 2 divided doses if needed. Patients w/ intravascular volume depletion: Initially, 25 mg once daily. Diabetic nephropathy in Type 2 diabetes mellitus Adult: Initially, 50 mg once daily, may increase to 100 mg once daily depending on BP response. Heart failure, Hypertension and Left Ventricular Hypertrophy, Stroke risk reduction of hypertensive or LVH patients: Adult: Initially, 50 mg once daily. Hydrochlorothiazide 12.5 mg daily should be added and/or the dose of Losartan should be increased to 100 mg once daily followed by an increase in hydrochlorothiazide to 25 mg once daily based on blood pressure response

Child Dose:
Hypertension <6 years: Safety and efficacy not established Child: >6 yr 20-50 kg: Initially, 0.7 mg/kg. Max: 50 mg/day; >50 kg: Initially, 1.4 mg/kg. Max: 100 mg/day.

Renal Dose:
Renal impairment: CrCl <20 ml/min: Initially 25 mg once daily.

Contraindication:
Losartan potassium is contraindicated in patients who are hypersensitive to the active ingredient or any component of the drug. Concomitant use w/ aliskiren in patients w/ diabetes and renal impairment (GFR <60 mL/min). Severe hepatic impairment. Pregnancy.

Quick Tips:
▶ Take it at the same time every day to help you remember to take it.
▶ It can make you feel dizzy for the first few days. Rise slowly if you have been sitting or lying down for a long time.
▶ Your doctor may get regular tests done to monitor the level of urea, creatinine, and potassium in your blood.
▶ Avoid taking anti-inflammatory medicines such as ibuprofen along with this medicine without consulting your doctor.
▶ Do not take Angilock 50 if you are pregnant or breastfeeding.
▶ Do not stop taking it suddenly without talking to your doctor.

Uses

Hypertension (high blood pressure)
Heart failure
Prevention of heart attack and stroke

Side Effects

Common
Dizziness
Decreased blood pressure
Hypoglycemia (low blood glucose level)
Increased potassium level in blood
Increased blood urea

Precautions

Volume-depleted patients including patients on high-dose diuretics. Patients w/ bilateral renal artery stenosis , aortic or mitral stenosis. Renal and mild to moderate hepatic impairment. Lactation. Monitoring Parameters Monitor BP, electrolytes and renal function. Lactation: Unknown if excreted in milk; not recommended